Yeah, I've had this happen before. When I first started leveling my pets the little low level mobs would come up and start missing me and I'd just kind of stare at them like " Are you serious" but I noticed that the critter I was fighting disappeared... And that was not going to sit well with me.
And thus the beginning of area wipes began. I would kill every mob I saw in the area to make sure it didn't have a path near me.
And I still do a lesser extreme version of that.
But just make sure
that when you are battling you try to get it done quickly in higher level areas else you'll lose a lot of rares and uncommons like I have to the random crap mandids who... I didn't even know were even in the area. (Although I think they find me on purpose)