I think I've spotted one...
Ti'un the wanderer Vs. a flyer with Alpha strike
Alpha Strike hits for 243 +162 if faster. Flying Vs. Aquatic is strong, usually hitting for around 650-700 non-crit.
It hits as hard as expected, until he uses his turtle shield ability, reducing hits by "up to 120ish" according to the tooltip.
As soon as he does that, Alpha Strike hits for around 240 damage

a reduction of major proportions!
Seems like his shield is either super tough, or it's applying base damage against flying mobs, which should have a damage bonus?